CONFERENCE
Program
Conference & Exhibition
June 10-12
Tutorials & Workshops
June 13
2025 PROGRAM
For both the conference program and the exhibition, the focus is on employing HPC in science, engineering, and business.
The ISC 2025 event consists of a conference and an exhibition. The conference program is divided into Invited, Contributed, and Vendor Sessions. Torsten Hoefler from ETH Zurich in Switzerland serves as the chair of the ISC 2025 Program. He is committed to highlighting the theme “Connecting the Dots” and highlighting the importance of HPC on science, engineering, and business.
TOPICS
ISC 2025 TOPIC AREAS
System Architecture & Hardware Components
- Beyond Moore’s Law
- Composable Disaggregated Infrastructure
- Data Center Infrastructure and Cooling
- Emerging Computing Technologies
- Extreme-scale Systems
- Heterogeneous System Architectures
- Interconnects and Networks
- Memory Technologies and Hierarchies
- Storage Technologies and Architectures
- Sustainability and Energy Efficiency
Programming Environments & System Software
- Compiler and Tools for Parallel Programming
- Energy Management
- HPC in the Cloud and HPC Containers
- Parallel File Systems
- Parallel Programming Languages
- Resource Management and Scheduling
- Runtime Systems for HPC
- System and Performance Monitoring
Algorithms, Methods & Performance
- Extreme-scale Algorithms
- Mixed Precision
- Novel Algorithms
- Numerical Libraries
- Optimizing for Energy and Performance
- Performance and Resource Modeling
- Performance Measurement
- Performance Tools and Simulators
Applications & Use Cases
- Application Workflows for Discovery
- Bioinformatics and Life Sciences
- Chemistry and Materials Science
- Computational Physics
- Earth, Climate and Weather Modeling
- Engineering
- Geosciences and Energy Generation
- Industrial Use Cases of HPC, ML and QC
- Visualization and Virtual Reality
Machine Learning & AI
- AI Applications powered by HPC Technologies
- Digital Twins and ML
- High-Performance Data Analytics
- HPC Simulations enhanced by Machine Learning
- HW and SW Design for Scalable Machine Learning
- Large Language Models and Generative AI in HPC
- ML Systems and Tools
Quantum Computing
- Integration of Quantum Computing and HPC
- Quantum Computing – Basics and Theory
- Quantum Computing – Technologies and Architectures
- Quantum Computing – Use Cases
- Quantum Program Development and Optimization
- Simulating Quantum Systems
Community & HPC
- Community Engagement
- Development of HPC Skills
- Diversity and Inclusion
- Education and Training
PROGRAM AT A GLANCE
The Invited Program Committee (IPC) ensures that all relevant topic areas in HPC systems and applications are addressed at ISC 2025.
Click on the image for a larger view
INVITED PROGRAM
The ISC Invited Program explores the developments and trends in HPC and adjacent technologies to allow users and vendors to understand how these technologies are coming together. Attendees can look forward to a good selection of topics and speakers consisting of senior and junior researchers from various geographies and research domains.
KEYNOTES

OPENING KEYNOTE
Tuesday, June 10, 9:15-10:15 am
HPC and AI: A Path Towards Sustainable Innovation
High performance computing (HPC) and artificial intelligence (AI) are intrinsically linked by their hardware, software, and the nature of their problem sets. They are also linked by their need to deliver highly energy-efficient computing at scale. As a consequence, HPC and AI are on a path toward convergence that will reshape much of the industry in the years ahead. The newer systems, such as Frontier and El Capitan in the United States and LUMI and HPC6 in Europe, are already paving the way by pushing the boundaries of performance while emphasizing energy efficiency.
In the opening keynote, AMD Chief Technology Officer and Executive Vice President Mark Papermaster will present his company’s vision of how the HPC-AI convergence will play out, and how energy efficiency can be enhanced through advancements in silicon, system design, software, and other technologies. He will also discuss the importance of collaboration and the need for an open ecosystem.

Director of Climate Physics Department, Max Planck Institute for Meteorology Hamburg, Germany
Midweek KEYNOTE
Wednesday, June 11, 5:05-5:50 pm
Climate change and AI are conspiring to create new markets in climate services: climate change contributes by making information, previously discounted by experience, more valuable; AI contributes by making the provision of this information scalable and affordable. The response to this new situation is redefining the climate computing landscape to meet three grand challenges: (1) to design and run more physical climate models at the scale of local impacts globally, across decades and scenarios; (2) to use their output — a complex hyperplane in a terra dimensional space — to train new types of foundation models; (3) to fine tune the models to map what is learned into the imagination of users, and then scale this across a very wide user community. The first two steps are computationally intensive, as they require access to exa-scale computing and data, but can be localized and intermittent. The third step involves structured human interaction and advanced AI capabilities, and must be continuous and distributed. This changing landscape of climate computing is reflected in initiatives like EVE, Destination Earth, and the Klima Hanse. In this talk, I detail this new landscape, the forces that are shaping it, and the ecosystem of services it entails.

CLOSING KEYNOTE
Thursday, June 12, 5:30-6:15 pm
Tackling Fragmentation in Exascale Supercomputing and Beyond
As we navigate the new age of supercomputing powered by artificial intelligence (AI), we find ourselves standing at the threshold of transformative computing power.
This leap has increased the complexity and diversity of high performance computing (HPC) systems. Hardware heterogeneity is on the rise, manifested at various levels – from different precision types of individual processors to processor classifications within nodes, as well as different architectures of clusters in different systems. Concurrently, the application domain is broadening, fueled by the escalating computational needs of multiple disciplines, the exponential growth in AI capabilities, and the convergence of HPC with AI methodologies. This expansion has led to significant fragmentation in system architecture and application requirements, and thus necessitating a wide array of computing resources and environments. To navigate this fragmentation, a collaborative co-design approach involving hardware, software, and application stakeholders is a must to bridge the divides. We need unified, portable programming models to handle varying precision and hardware types. Common frameworks are also required for application development across different systems. Furthermore, the architecture of software infrastructures must be meticulously crafted to standardize both systems and applications, ensuring portable, high-performance, and system-agnostic support. By comprehensively addressing these challenges, we can harness the full potential of the post-exascale era, charting a new course for the future of supercomputing.
The three ISC keynote presentations offer unique insights each day, featuring renowned experts in HPC, AI, and IT.
Midweek Keynote: Details on speaker and topic coming soon. Stay tuned!
PANELS
Panels bring together groups of experts to discuss key topics, share insights, and engage with audience questions. In a Fishbowl panel, audience members can actively join the discussion, rotating throughout the session to contribute diverse perspectives.Â
INVITED TALKS
Invited Talks feature formally invited speakers to present valuable insights on the 2025 conference topic areas, followed by Q&A sessions moderated by research peers.
HPC AROUND THE WORLD
The HPC Around the World sessions aim to provide comprehensive insights into HPC initiatives and applications across different global regions, including Europe, the Asia-Pacific, Latin America, Africa, and the Middle East, highlighting their status, challenges, and opportunities.
HPC in Europe
The session ‘HPC in Europe‘ will take a look at the current state of HPC, AI, and Quantum Computing across the continent. The EuroHPC Joint Undertaking will present its latest initiatives to provide leading-edge HPC resources for AI and scientific simulation applications. Additionally, representatives from leading HPC sites in Germany, Switzerland, and the UK will share recent achievements and discuss opportunities for users.
HPC in Asia-Pacific
The session ‘HPC in Asia-Pacific‘ will explore the evolving landscape of national High-Performance Computing programs, highlighting both successes and challenges in planning, resourcing, and collaboration. Experts from across the region – including China, India, Japan, Singapore, South Korea, and Taiwan – will share insights into cross-sector partnerships and international collaboration, workforce development, and emerging directions for HPC.
HPC in Africa, Latin America & Middle East
The session ‘HPC in Africa, Latin America & Middle East‘ will feature experts from Brazil, Morocco, South Africa, Egypt, Saudi Arabia, and the UAE. Speakers will discuss the growth of national HPC program, adressing successes and challenges in planning, resourcing, and collaboration. The session will also highlight the impact of cross-sector and international collaboration, workforce development, and emerging opportunities for HPC.
WALKING TALK
This year, we are introducing a new format to bring more variety and encourage greater interaction. Instead of presenting in a traditional conference hall, the speaker will guide attendees through the exhibition, stopping at booths that align with a common theme. This year’s theme is sustainability!

Program Chair
Professor of Computer Science, ETH Zurich, Switzerland

Program Deputy Chair
Manager Workflows & Distributed Computing Group, BSC, Spain
PROGRAM CHAIR & DEPUTY
“We look forward to seeing everyone interested in HPC and AI at the 40th edition of ISC. If you have a passion for big iron, whether you’re a student, a researcher, a decision-maker, or a politician, we welcome your participation.“ Torsten Hoefler
INVITED PROGRAM COMMITTEE
The Invited Program Committee (IPC) ensures that all relevant topic areas in HPC systems and applications are addressed at ISC 2025.

System Architecture & Hardware Components

Programming Environments & System Software

Algorithms, Methods & Performance

Applications & Use Cases

Machine Learning & AI

Quantum Computing

HPC in Asia-Pacific (HPC Around the World)

HPC in Africa, Latin America & Middle East (HPC Around the World)

HPC in Europe (HPC Around the World)

HPC Around the World (Europe)
Additionally, the IPC consists of the following members:
- ISC 2025 Program Chair – Torsten Hoefler (ETH Zurich, Switzerland)
- ISC 2025 Program Deputy Chair – Rosa Badia (BSC, Spain)
- ISC Program TeamÂ
HELP SHAPE THE INVITED PROGRAM AT ISC!
ISC encourages the community to take part in shaping the Invited Program. Share your nominations for speakers, panelists and chairs, especially talented early-career individuals, including women and researchers from underrepresented regions, who deserve to be recognized on a global stage.

CONTRIBUTED PROGRAM
Scientists, researchers and engineers of all career levels are invited to contribute to the program. Their submissions will have an impact on the conference program.
The submission process is overseen by a chair and deputy chair, who are aided by an international committee with expertise in their respective fields. This committee is responsible for evaluating and approving the submissions, as well as putting together a diverse program.
RESEARCH PAPER
The research papers sessions provide great opportunities for engineers and scientists from academia, industry, and government to come together and exchange ideas on significant topics, trends, and discoveries that shape the future of high performance computing (HPC), machine learning, data analytics, and quantum computing.
RESEARCH POSTER
The ISC research poster session provides a global platform to showcase latest research results, projects, and innovations.
PROJECT POSTER
We initiated the project poster session to provide researchers with a platform for exchanging information. Attendees can use the project posters to gain an overview of new developments, HPC research, and engineering activities.
WOMEN IN HPC POSTER
The WHPC poster session at ISC is dedicated to women and individuals from underrepresented groups who are students or are in the early stages of their HPC careers, typically within the first 5 years post-graduation or via a career transition into the field of supercomputing.
BIRDS OF A FEATHER
Birds of a Feather (BoF) sessions offer an informal platform for dynamic discussions among peers, experts, leaders, and anyone from the HPC community with shared interests.
Each 60-minute BoF session addresses current HPC topics and is guided by one or more experts in their field.
TUTORIALS
The ISC tutorials are interactive courses and collaborative learning experiences focusing on key topics of high performance computing, machine learning, data analytics and quantum computing.
Renowned experts in their respective fields will give attendees a comprehensive introduction to the topic as well as providing a closer look at specific problems.
ACCEPTED TUTORIALS
- Advanced MPI Programming
- Advanced OpenMP: Performance and 6.0 Features
- An Introduction to Developing Highly Parallel Applications Using C++ and SYCL
- Bootstrapping and Cluster DevOps with OpenCHAMI
- Containers Everywhere - HPC, Cloud and Edge
- Core-Level Performance Engineering
- Determining Parallel Application Execution Efficiency and Scaling Using the POP Methodology
- Distributed Deep Learning on GPU-based Clusters
- Efficient Distributed GPU Programming for Exascale
- Energy Monitoring and Optimization with EAR
- Flux: Next-Generation Workload Management for High Performance Computing and Cloud
- Heterogeneous Distributed Computing with Classical and Quantum Compute Resources in the Cloud
- Leveraging and Evaluating LLMs for HPC Research
- Leveraging SmartNICs for HPC Applications
- Managing HPC Software Complexity with Spack
- Mastering Tasking with OpenMP 6.0
- Modern Mixed-Precision Methods: Hardware Perspectives, Algorithms, Kernels, and Solvers
- Object Storage for High Performance I/O
- Performance Engineering for Sparse Linear Solvers
- Portable GPU Acceleration of HPC Applications with Standard C++26
- Principles and Practice of Scalable and Distributed Deep Neural Networks Training and Inference
- Programming Novel AI Accelerators for Scientific Computing
- Programming Quantum – Classical Architectures: Preparing for Quantum Computing Research Using GPU and QPU Resources
- Quantum Optimization ISC 2025
WORKSHOPS
The ISC workshops aim to offer attendees a concentrated and comprehensive forum for presentations, conversations, and engagement on a specific topic. Two types of workshops will be hosted.
WORKSHOPS WITH PROCEEDINGS
Workshops focused on disseminating their own call for papers and implementing a peer-review process. These workshops have specific requirements and a submission schedule. Papers that are accepted will be published in post-conference proceedings.
- 6th ISC HPC International Workshop on “Monitoring & Operational Data Analytics”
- 9th International Workshop on In Situ Visualization
- Energy Efficiency with Sustainable Performance: Techniques, Tools, and Best Practices
- Fifth International Workshop on Computational Aspects of Deep Learning
- Fifth workshop on Compiler-assisted Correctness Checking and Performance Optimization for HPC
- Fifth Workshop on Communication, I/O, and Storage at Scale on Next-Generation Platforms - Scalable Infrastructures -
- Fifth Workshop on Interactive and Urgent HPC
- HPC on Heterogeneous Hardware (H3)
- International Workshop on RISC-V for HPC at ISC
- The First International Workshop on Foundational Large Language Models Advances for HPC
REGULAR WORKSHOPSÂ
Workshops without a call for papers and no post-conference proceedings.
- 2nd Workshop on Readiness of HPC Extreme-scaling Applications
- 4th International Workshop on Sustainable Supercomputing
- 4th Workshop on Quantum and Hybrid Quantum/Classical Computing Approaches
- A2SD: Advancing Autonomous Scientific Discovery Workshop
- Arm HPC User Group (AHUG) at ISC 2025
- Hardware Modularity for Practical Heterogeneous HPC
- High Performance Container Workshop 2025
- HPC I/O in the Data Center
- PPP 01: First Workshop on the Pain of Parallel Programming
- QRUCH : Quantum Resources for Unified Computing Hub
- Research Software Engineering in High-Performance Computing - Tools and Techniques for Continuous Integration and Benchmarking
- SuperCompCloud: 9th International Workshop on Interoperability of Supercomputing and Cloud Technologies combined with OpenCHAMI
- The Future of Benchmarks in Supercomputing
- Trillion Parameter Consortium Workshop: Synthetic Data, Trust, and Scale when Advancing Reliable AI Models for Science
ISC 2024 WORKSHOP PROCEEDINGS
The ISC 2024 Workshop Proceedings are available in Springer’s Lecture Notes in Computer Science (LNCS). Click below to explore the papers and gain valuable insights.



Contact
MS. ISABEL GRÄBNER​
Conference Program Manager
MR. GEORG HAGER
Contributed Program Advisor


Contact
MS. ISABEL GRÄBNER​
Conference Program Coordinator​
MR. GEORG HAGER
Contributed Program Advisor
VENDOR PROGRAM
The ISC Vendor Program is a platform for commercial organizations to showcase their offerings and business strategies. It complements the ISC Exhibition and allows companies to demonstrate their current and upcoming solutions. As a result, HPC users from science, engineering, and business can gain a comprehensive understanding of the products and services available in the market, as well as what they can anticipate in the future.
VENDOR ROADMAPS
VENDOR SHOWDOWN
The well-liked Vendor Showdown features presentations by influential figures in the HPC industry. The showdown is divided into two simultaneous sessions, with each speaker given a few minutes to showcase their organization’s latest strategies, products, and research. Following this, a group of expert moderators will engage them in a lively discussion by asking thought-provoking questions.
HPC SOLUTIONS FORUM
The HPC Solutions Forum allows companies and research institutions to discuss topics such as cloud computing, machine learning, performance optimization, networks, composability, and data management.
Each speaker has a 20-minute slot to discuss their perspective on one to three topics and how it ties into their organization’s technological and business strategies. All talks will be held in person at the forum.
ONLINE INNOVATION SHOWCASE
FIRST-TIME EXHIBITOR PITCH
First-time exhibitors will have the opportunity to present themselves in a one-minute introduction.
The introduction is intended to provide a brief overview of the company’s mission, values, and focus, as well as to provide insight into recent initiatives, projects, or offerings.

STEERING COMMITTEE
The ISC 2025 Steering Committee provides guidance on the conference program and helps enhance the visibility, recognition, and growth of ISC within industry, research, and academia.
ISC 2025 COMMITTEE MEMBERS
- Sadaf Alam, University of Bristol, UK (Research Poster Chair)
- Hartwig Anzt, Technical University of Munich, Germany (Tutorial Deputy Chair)
- Rosa Badia, Barcelona Supercomputing Center, Spain (Program Deputy Chair)
- Frank Baetke, European Open File Systems Association, Germany (ISC Fellow)
- Prasanna Balaprakash, ORNL, USA (Invited Program Committee Topic Area Chair)
- Florian Berberich, PRACE
- Sanjukta Bhowmick, University of North Texas, USA (Invited Program Committee Topic Area Chair)
- Gianfranco Bilardi, University of Padova, Italy (Project Poster Deputy Chair)
- David Boehme, Lawrence Livermore National Laboratory, USA (BoF Chair)
- Taisuke Boku, University of Tsukuba, Japan (Invited Program Committee Topic Area Chair)
- Ron Brightwell, Sandia National Laboratories, USA (Invited Program Committee Topic Area Chair)
- Erin Carson, Charles University, Czech Republic (Proceedings Deputy Chair)
- Jack Dongarra, University of Tennessee, USA (ISC Fellow)
- Horst Gietl, Germany (ISC Fellow)
- Pauline Gounaud, EuroHPC Joint Undertaking, Luxemburg
- Torsten Hoefler, ETH Zurich, Switzerland (Program Chair)
- Tanzima Islam, Texas State University, USA (Research Poster Deputy Chair)
- Hatem Ltaief, KAUST, Saudi Arabia (Research Paper Deputy Chair)
- Yutong Lu, Sun Yat-Sen University East Campus, China (ISC Fellow)
- Thomas Ludwig, Universität Hamburg & DKRZ, Germany (ISC Fellow)
- Satoshi Matsuoka, Riken Center for Computational Science, Japan (ISC Fellow)
- Diana Moise, HPE, Switzerland (Tutorial Chair)
- José Moreira, IBM, USA (Project Poster Chair)
- Wolfgang Nagel, Technische Universität Dresden, Germany (ISC Fellow)
- Sarah Neuwirth, Johannes Gutenberg University Mainz, Germany (Workshop Chair)
- Manish Parashar, University of Utah, USA (Invited Program Committee Topic Area Chair)
- Arnab K. Paul, Birla Institute of Technology and Science, India (Workshop Deputy Chair)
- Amanda Randles, Duke University, USA (Research Paper Chair)
- Laura Schulz, Leibniz Supercomputing Centre, Germany (Invited Program Committee Topic Area Chair)
- Horst Simon, ADIA Lab, Abu Dhabi (ISC Fellow)
- Happy Sithole, National Integrated Cyber-Infrastructure System, South Africa (HPC Around the World Chair)
- Thomas Sterling, Indiana University, USA (ISC Fellow)
- Mark Stickells, Pawsey Supercomputing Centre, Australia (HPC Around the World Chair)
- Erich Strohmaier, USA (ISC Fellow)
- Carsten Trinitis, Technical University of Munich, Germany (BoF Deputy Chair)
- Tobias Weinzierl, Durham University, UK (Proceedings Chair)
Awards




ISC High Performance bestows awards annually to recognize research excellence by individuals and research groups from the global HPC communities.

JACK DONGARRA EARLY CAREER AWARD
The ISC High Performance Jack Dongarra Early Career Award and Lecture Series
is an annual event that honors the remarkable contributions of Professor
Jack Dongarra to the field of high performance computing and to the community.
The award includes a certificate of recognition and a cash prize of 5,000 Euros.

HANS MEUER AWARD
The award honors the best research paper submitted to the conference’s Research Papers Committee. This award has been introduced in the memory of the late Dr. Hans Meuer, general chair of the ISC conference from 1986 through 2014, and co-founder of the TOP500 project.
The Hans Meuer Award includes a cash prize of 3,000 Euros and an award certificate.

Winner 2025
The paper selected as the winner of the ISC 2025 Hans Meuer Award is:
Towards a Unified Architectural Representation in HPCQC: Extending sys-sage for Quantum Technologies.
Authored by Durganshu Mishra, Stephan Vanecek, Jorge Echavarria, Xiaolong Deng, Burak Mete, Laura Schulz and Martin Schulz (Technical University Munich and Leibniz Supercomputing Center)

RESEARCH POSTER AWARD
The research poster award recognizes three outstanding research posters as selected by members of the posters committee.
The award includes a cash prize of 500 Euros (first place), 300 Euros (second place) and 200 Euros (third place)
STUDENT PROGRAM
STUDENT PROGRAM
The ISC Student Program offers students exposure to high performance computing, artificial intelligence, data analytics and quantum computing. The program is aimed at graduate and undergraduate students.

The Student Cluster Competition is one of our more popular programs. It invites university student teams from around the world to compete online and in real-time to showcase their own cluster system designs while striving for the highest performance.

Help us to organize the 2025 event, and in return, you shall gain exclusive access to tutorials, conference sessions, workshops, the exhibition, and even selected evening events.