EXPLORE
QUANTUM COMPUTING
June 10 – 13, 2025
CCH, Hamburg
GERMANY
quantum COMPUTING AT ISC 2025
Quantum computing (QC) has the potential to solve what are now intractable problems on classical computers, even the most powerful supercomputers. For example, there are many applications in both life science and materials science that lend themselves to QC-powered solutions. This is particularly relevant for applications where the underlying physics takes place at the size and timescale of the quantum realm.
That does not mean that classical computing is coming to an end. Indeed, the integration of traditional high performance computing (HPC) with QC is increasingly viewed as a path toward unlocking the potential of quantum computers, while enhancing the power and scope of HPC systems. This integrated model makes QC particularly relevant to our community and to this event.
ISC 2025 is a great opportunity for businesses, research organizations, service providers, or users like you who are interested in how our community can be used as a springboard to explore QC research and commercial applications. The event offers a wealth of resources and information on how QC is becoming an integral part of our industry.
OFFERINGS AT ISC
The event features multiple sessions, workshops, and tutorials in the QC space, as well as an exhibition showcasing companies and research organizations from around the world dedicated to providing cutting-edge hardware, software, and services for the nascent quantum computing market. Here is a brief breakdown of the various QC-focused offerings at ISC 2025:
INVITED TALK
From Qubits to Breakthroughs: The Path to Practical Quantum Applications (Wednesday, June 11)
Quantum computing offers a compelling alternative to conventional computing. This is especially relevant in multiscale and multiphysics problems, which abound in complex condensed matter systems within both the life and materials sciences. Here, we face the challenge of studying sizeable quantities of matter using a combination of length and time scales in which different laws of physics apply. At the smallest sizes and timescales, where quantum mechanics rules, particularly challenging parts of a system may be best studied via computations performed on quantum processing units (QPUs) coupled directly to nodes on a supercomputer. This session explores such hybrid computing architectures and the kind of applications we can expect to run on them.
PANEL
From Qubits to Insights: The Role and Roadmap of Hybrid Quantum-HPC Software (Thursday, June 12)
The integration of QC with HPC is critical to unlocking quantum computing’s full future potential for real-world applications and discovery. But the software stack bridging various quantum hardware to HPC systems remains a work in progress. This panel will explore the current state, key challenges, and future directions of hybrid QC-HPC software, covering the spectrum from low-level hardware abstraction to high-level application development.
Birds of a feather (BOF)
Scientific Computational Workflows in Hybrid Quantum-Classical Environments (Thursday, June 12)
Quantum computing is being explored as the next high-impact extension to the computing spectrum, particularly with integration into supercomputers and cloud environments. The successful interoperability between classical and quantum systems will depend on middleware interacting with heterogeneous hardware and their associated software stacks and data management methods. The most realistic approach towards leveraging QC in the near-term involves loosely-coupled integration of the classical and quantum devices through traditional computing networks. Although these solutions can offload computation to quantum systems, approaches toward high-level hybrid programming and workflow management are still lacking. This Birds-of-a-Feather session aims to develop hybrid quantum-classical workflows that reconcile quantum and classical systems and software stacks.
Tutorials
Friday, June 13
Please note: The tutorial pass also provides access to workshops!
Quantum Optimization
Quantum computing is a rapidly evolving technology with significant potential, particularly for
solving optimization problems. Hard-to-solve classical challenges, such as graph-based problems,
hold high practical relevance. A notable example is task mapping, where quantum approaches
could provide groundbreaking solutions. Currently, hybrid methods such as the Quantum Approx-
imate Optimization Algorithm (QAOA) are especially promising as they circumvent some of the
disadvantages of noisy intermediate-scale quantum computers.
Programming Quantum – Classical Architectures: Preparing for Quantum Computing Research Using GPU and QPU Resources
The rapid advancement of quantum computing necessitates the development of hybrid computing architectures, where Quantum Processing Units (QPUs), Graphics Processing Units (GPUs), and Central Processing Units (CPUs) collaborate to tackle complex computational problems. As quantum applications continue to emerge, researchers must navigate the intricate landscape of hybrid quantum-classical computing. This tutorial is designed to equip participants with the necessary skills to leverage QPU and GPU resources for conducting quantum computing research.
Heterogeneous Distributed Computing with Classical and Quantum Compute Resources in the Cloud
Classical Quantum Monte Carlo (QMC) methods leverage High Performance Computing (HPC) resources to simulate complex quantum many-body systems. Quantum computation has the potential to provide new routes to tackling these problems. Recently, a series of hybrid quantum-classical QMC methods have been proposed. These approaches seek to advance classical QMC by augmenting the classical algorithm with a quantum processing unit.
WORKSHOPS
Friday, June 13
4th Workshop on Quantum and Hybrid Quantum/Classical Computing Approaches
Building on the success of the last three years, the 4th Quantum and Hybrid Quantum-Classical Computing Approaches workshop continues to explore the forefront of quantum computing and its integration with classical systems. This year, in addition to covering benchmarking of quantum architectures and software, we are expanding our focus to include emerging areas and advancements in quantum technology, such as quantum error correction.
QRUCH: Quantum Resources for Unified Computing Hub
Quantum Computing is not a completely new topic: it was introduced in 1981 during a conference at MIT, but it really came under the spotlight as Peter Shor released his famous algorithm capable of breaking RSA encryption with tremendous acceleration. The domain remained a bit theoretical, studied in mathematical computer science, until a few years ago when actual Quantum Computers arrived on the market providing real (but yet limited) quantum computing resources.
In the very last years, Quantum Computers gained more computing power, and they started to be deployed inside HPC centers while also becoming available on cloud based platforms.
RESEARCH PAPER
Tuesday, June 10 – Wednesday, June 11
HANS MEUER AWARD WINNER: Towards a Unified Architectural Representation in HPCQC: Extending sys-sage for Quantum Technologies
Quantum Computing (QC) presents a significant departure from and substantial parallels to classical computing. Some such parallels include the need to understand topology and system characteristics information and make that available to users as well as other system components like compilers, runtimes, and schedulers.
Telemetry for Quantum Systems in HPC Centers
Quantum systems have traditionally operated within highly controlled laboratory environments to minimize internal noise and maximize stability. However, when these systems are integrated into High Performance Computing (HPC) environments and setup for continuous operation, they encounter significantly higher levels of external noise and instability coupled with higher demands. This paper introduces a comprehensive framework to counter the challenges of maintaining the stability of operational quantum computers in such noisy HPC settings.
Quantum-Accelerated Supercomputing Atomistic Simulations for Corrosion Inhibition
This work demonstrated a proof-of-concept use case for the emerging quantum-centric supercomputing approaches combining HPC resources with quantum computers. We presented a systematic implementation of hybrid quantum-classical computational method for accelerating atomistic simulations studying corrosion inhibition.
Exhibits
June 10 – June 12
There are more than a dozen exhibitors offering quantum computing hardware, software, and/or services. Among them are the following: Classiq, IBM, IonQ, IQM Quantum Computers, PlanQC GmbH, Qilimanjaro Quantum Tech, Quandela, Quantinuum, QUDORA, QuEra Computing Inc, QuiX Quantum, and TreQ.
In addition to vendors, a number of HPC research centers exhibiting at ISC 2025 are also developing QC-based solutions. While these organizations do not offer commercial products, they often provide open source software that is available to developers, as well as opportunities to collaborate with companies looking to build products and services with quantum computing technologies.